SURVEY: Temperature Indicators & Platelet Bacterial Contamination

“Sepsis from a bacterially contaminated platelet unit represents the most frequent infectious complication from any blood product today.”1

Would a temperature indicator help your blood bank improve quality control, patient outcomes and platelet discard rates?
Take the Survey: Click Here

Because platelets are stored at room temperature, their shelf life is limited to 5 days due to the risk for bacterial growth during storage. Bacterial contamination of platelets is a major concern because of the rich plasma environment at room temperature. All apheresis platelets are sampled and cultured for bacteria growth prior to issue. Platelets that have exceeded the AABB guideline temperature range (20 – 24°C) are at greater risk for elevated bacterial counts. When this happens, not only is the patient risk high, but there are also intense challenges on the blood bank to maintain adequate platelet supplies AND assure patient safety.

As a major manufacturer of temperature indicators for healthcare applications, we are interested to hear from you about the possible application of a temperature indicator for platelets (PLTs). For that reason, we’re conducting a survey.

Publications on Platelets

Just this past November, AABB published clinical guidelines on appropriate use of platelet transfusion in adult patients, developed by a panel of twenty-one experts (named in the article). These guidelines appear in the February 2015 issue of Annals of Internal Medicine. While the article provides six recommendations specific to platelets and transfusions, it states early in the article that:

“Sepsis from a bacterially contaminated platelet unit represents the most frequent infectious complication from any blood product today.”1

In a 2011 article in Transfusion, the author noted that “…outdating PLTs is a financial burden and a waste of a resource.”2

In response to this recent attention to platelets, we’ve considered whether an irreversible temperature indicator for platelets would help protect patients AND reduce the financial burden associated with outdated PLTs.

Please CLICK HERE to take our survey
and share your thoughts.

In this short survey, we’d like to learn more about your blood bank’s platelet inventory management – and to get your ideas on the possible value of a platelet temperature indicator.

After the survey closes, we’ll publish the responses so you can learn from each other. Survey participants will receive a pre-release of the results – and also be entered in the AABB drawing in Anaheim to win a FREE Val-A-Sure Cooler Validation Kit!

Thank you for taking time to participate in the survey. We look forward to your input, and are happy to provide a forum for sharing ideas in VUEPOINT.

Jeff Gutkind
jeffg@temptimecorp.com

For the entire AABB Guidelines: A Clinical Practice Guideline From the AABB.

Sources:
1 Stramer SL. Current risks of transfusion-transmitted agents: a review. Arch Pathol Lab Med. 2007; 131:702-7.

2 Fuller AK, Uglik KM, Braine HG, King KE. Transfusion. 2011 Jul;51(7):1469-76. doi: 10.1111/j.1537-2995.2010.03039.x. Epub 2011 Feb 8.

COMZ VUEPOINT (doc. 2371)

Reduce RBC and FFP Waste, Improve ROI

Learn more from this Blood Transport and Storage Initiative that resulted in significant ROI

by Jeff Gutkind, Business Development Manager

I recently read an article in the journal Transfusion1 in reference to reducing red blood cell (RBC) and plasma (FFP) waste.  The study showed significant reduction in RBC and FFP waste by using a new blood transport and storage system, and a significant return on their investment in the new system (estimated savings of $9000/month for their institution).

While the article doesn’t speak to temperature indicators, it does seem to validate that there is a trend toward cooler storage in the OR being considered “intraoperative storage,” which is significant.

For those of us sensitive to blood waste (and associated costs) due to time-temperature issues, this study has a wealth of valuable information and powerful messages:The article cites a national waste rate for hospital-issued blood products ranging from 0% to 6%, and a common reason for blood waste being inadequate intraoperative storage.2

  • The article describes how most of their blood waste was from either temperature or time (away from the blood bank) excursions, and that 70% of those losses came from blood product issued to the OR in coolers.
  • In the second paragraph they state that “AABB standards require red blood cell and plasma units to be maintained at a temperature of 1-10°C during transport and 1-6°C during intraoperative storage.
  • They go on to state (under Materials and Methods) that “holding product in the OR represents a storage condition“….. and “the storage (1-6°C), not the more lenient transport (1-10°C) temperature range needed to be maintained.”

Their previous procedure was to issue blood products to the OR in off-the-shelf commercial coolers that were validated to hold product at 1-10°C for 8 hours. They changed to a new, more expensive cooler that incorporated specialty phase change material that is validated to hold 1-6°C for 18 hours. As a result of the new system and strategy, they have improved their “storage” compliance to 1-6°C and reduced waste from 1.20% to 0.06%, which they calculate to save the $9,000 per MONTH.

The result of this study suggests that incorporating a new, longer duration blood shipping and storage container has allowed the OR to store blood for up to 18 hours at 1-6°C while meeting AABB’s more strict guidelines and has produced significant cost savings and notable return on investment 

It would be interesting to see the savings if they incorporated a Safe-T-Vue 6 indicator in this study.

REFERENCES:

1. Brown MJ, Button LM, Badjie KS, Guyer JM, Dhanaroker SR, Brach EJ, Johnson PM, Stubbs JR. Implementation of an intraoperative blood transport and storage initiative and its effect on reducing red blood cell and plasma waste, Transfusion 2014;54: 710-07.

2. Heltimiller ES, Hill RB, Marshall CE, Parsons FJ, Berkow LC, Barrasso CA, Zink EK, Ness PM. Blood wastage reduction using Lean Sigma methodology. Transufions 2010;50: 1887-96.